It is marketed as a prescription drug under the trade name xenical by roche in most countries, and is sold over-the-counter as alli by glaxosmithkline in the united kingdom and the united states. Its primary function is preventing the absorption of fats from the human diet by acting as a lipase inhibitor, thereby reducing caloric intake.
Xenical orlistat belongs to a class of medications known as anti-obesity agents, specifically gastrointestinal lipase inhibitors. When combined with a mildly reduced-calorie diet that contains no more than 30 of calories from fat, orlistat is used to help obese people lose weight and maintain weight loss.
Webmd provides important information about xenical oral such as if you can you take xenical oral when you are pregnant or nursing or if xenical oral.
Volunteers, xenical (120 mg three times a day) did not significantly affect the balance of calcium, magnesium, phosphorus, zinc, copper, and iron. Pediatrics in a 3-week study of 32 obese adolescents aged 12 to 16 years, xenical (120 mg three times a day) did not significantly affect the balance of calcium, magnesium, phosphorus, zinc, or copper.
Orlistat pregnancy warnings neither embryotoxicity or teratogenicity have been observed at doses 23 (rats) and 47 (rabbits) times the calculated daily human dose. Administration to rats from late gestation to weaning at 50 times the recommended human dose did not affect pup survival or development.
Xenical and pregnancy an overview xenical is a prescription weight loss aid that is likely safe for use during pregnancy. When given to pregnant animals, the drug did not cause any problems.
Orlistat is contraindicated for use during pregnancy because weight loss offers no potential benefit to a pregnant woman.
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Safety contraindications of xenical in the first trimester it is important for a woman who is pregnant to be aware of the potential effects that any medication, whether it is a prescription medication like xenical or whether it is an over-the-counter medication, will have on her pregnancy.
Safe use of orlistat during pregnancy has not been established.
Xenical is indicated for obese patients with an initial body mass index (bmi) 30 kgm2 or 27 kgm2 in the presence of other risk factors (e. Important safety information xenical is contraindicated in patients who are pregnant.).
Known hypersensitivity to xenical or to any component of this product (4).
The safety of xenical in pregnancy and nursing mothers has not been determined. Our xenical side effects drug center provides a comprehensive view of. Advice and warnings for the use of orlistat during pregnancy.
Find patient medical information for xenical oral on webmd including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Weight loss before art treatment can significantly improve pregnancy rates andor live births. During the years 1998-2011, among 392,126 infants born, 509 had been exposed to antiobesity drugs in early pregnancy 248 to orlistat, 242.
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